Hisayo Mochizuki as Purin Fon/Mew Purin
Junko Noda as Zakuro Fujiwara/Mew Zakuro
Kumi Sakuma as Lettuce Midorikawa/Mew Lettuce
Saki Nakajima as Ichigo Momomiya/Mew Ichigo
Yumi Kakazu as Mint Aizawa/Mew Mint
Hikaru Midorikawa as Keiichiro Akasaka
Junko Noda as R2000/Masha
Kouichi Toochika as Ryou Shirogane
Megumi Ogata as Masaya Aoyama
Akemi Kanda as Bad Girl (Episode 3)
Akemi Okamura as Mariko (Episode 30)
Akiko Nakagawa as Chancha (Episode 20),
Moe Yanagida, Takashi (Episode 19)
Akira Ishida as Shunsuke (Episode 30)
Asuka Tanii as Hanacha (Episode 20)
Ayako Kawasumi as Jacqueline (Episode 29)
Daisuke Sakaguchi as Quiche
Fumiko Orikasa as Iruka (Episode 19)
Hikaru Midorikawa as Piano Ghost (Episode 4)
Junko Minagawa as Young Ryou Shirogane (Episode 36)
Katsuyuki Konishi as Michelle (Episode 29),
Shintaro Momomiya
Kentarou Itou as Norihiro Edomurasaki (Episode 16)
Kiyomi Asai as Announcer (Episode 1),
Bad Girl (Episode 3),
Honcha (Episode 20),
Tart
Kouji Tsujitani as Doctor Shirogane (Episode 36)
Kousuke Okano as Masazou Aoyamada (Episode 8)
Kumiko Takizawa as Mrs. Ijuuin (Episode 29)
Kurumi Mamiya as Momoka (Episode 35)
Maria Kawamura as Rei Nishina (Episode 14)
Masaya Onosaka as Asano-kun (Episode 29)
Megumi Ogata as DeEpisode Blue
Michiko Neya as Lettuce's Mother (Episode 34)
Nobuo Tobita as Lettuce's Father (Episode 34)
Nobutoshi Canna as Pie
Rie Etou as Mary McGuire (Episode 6)
Rieko Takahashi as Ryou's Mother (Episode 36)
Rika Komatsu as Lucha (Episode 20), Pudding's Mother
Rina Mizuhara as Baya
Sachiko Kojima as Tsukiko (Episode 24)
Satsuki Yukino as Kindergarten Teacher (Episode 20)
Souichiro Hoshi as Seiji Aizawa
Takako Honda as, Bad Girl (Episode 3),
Sakura Momomiya, Tochiya (Episode 19)
Tomoe Hanba as Kanna Saionji (Episode 32),
Satsuki (Episode 16)
Tomoko Kaneda as Heicha (Episode 20, 33),
Miwa Honjou
Tomoko Kawakami as Ayano Uemura (Episode 39)
Toshiyuki Morikawa as Ron YuEpisodeing (Episode 33)